ABSTRACT
Background: Genital tuberculosis [GTB] is an important cause of female infertility, especially in developing countries. The positive results of polymerase chain reaction [PCR] in endometrial GTB in the absence of tubal damage raise the possibility of the detection of sub-clinical or latent disease, with doubtful benefits of treatment
Objective: To evaluate the mycobacterium tuberculosis infection in endometrial biopsy samples collected from unexplained infertile women attending Yazd Research and Clinical Center for Infertility by using PCR techniques
Materials and Methods: In this cross sectional study, 144 infertile women with unexplained infertility aged 20-35 years old and normal 1-listro-saplango graphy findinus were enrolled. Endometrial biopsy samples from each participant were tested fbr mycobacterium tuberculosis detecting by PCR. In 93 patients, peritoneal fluid was also taken for culture and PCR
Results: The PCR results of endometrial specimens were negative in all cases, demonstrating that there was no GTB infection among our patients
Conclusion: Our results showed that GTB could not he considered as a major problem in women with unexplained infertility. Although, studies have indicated that PCR is a useful method in diagnosing early GTB disease in infertile women with no demonstrable evidence of tubal or endometrial involvement